Zanocin may be available in the countries listed below.
Ofloxacin is reported as an ingredient of Zanocin in the following countries:
International Drug Name Search
In the US, Actiq (fentanyl systemic) is a member of the drug class narcotic analgesics and is used to treat Breakthrough Pain and Pain.
US matches:
UK matches:
Fentanyl is reported as an ingredient of Actiq in the following countries:
Fentanyl citrate (a derivative of Fentanyl) is reported as an ingredient of Actiq in the following countries:
International Drug Name Search
Glossary
| SPC | Summary of Product Characteristics (UK) |
Genesis Xtra Drench may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Abamectin is reported as an ingredient of Genesis Xtra Drench in the following countries:
Closantel is reported as an ingredient of Genesis Xtra Drench in the following countries:
International Drug Name Search
Plidex may be available in the countries listed below.
Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Plidex in the following countries:
International Drug Name Search
Zienam may be available in the countries listed below.
Cilastatin sodium salt (a derivative of Cilastatin) is reported as an ingredient of Zienam in the following countries:
Imipenem monohydrate (a derivative of Imipenem) is reported as an ingredient of Zienam in the following countries:
International Drug Name Search
Zolpidem-1A Pharma may be available in the countries listed below.
Zolpidem tartrate (a derivative of Zolpidem) is reported as an ingredient of Zolpidem-1A Pharma in the following countries:
International Drug Name Search
Treating occasional sleeplessness and reducing difficulty falling asleep.
Diphenhydramine is an antihistamine. It works in the brain to cause drowsiness.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Diphenhydramine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Diphenhydramine.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Diphenhydramine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Diphenhydramine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Diphenhydramine.
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Dizziness; drowsiness; dry mouth, throat, and nose; thickening of mucus in nose or throat.
Severe allergic reactions (difficulty breathing; hives; itching; tightness in the chest; rash; swelling of the mouth, face, lips, or tongue); decreased alertness; excitability; fast heartbeat; hallucinations; seizures; tightness or pounding in the chest; tremor; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.
Store Diphenhydramine at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), or according to the directions on the package label. Store in the original package or container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diphenhydramine out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Diphenhydramine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Zerocid may be available in the countries listed below.
Omeprazole is reported as an ingredient of Zerocid in the following countries:
International Drug Name Search
Zamec may be available in the countries listed below.
Ranitidine hydrochloride (a derivative of Ranitidine) is reported as an ingredient of Zamec in the following countries:
International Drug Name Search
Terry White Chemists Simvastatin may be available in the countries listed below.
Simvastatin is reported as an ingredient of Terry White Chemists Simvastatin in the following countries:
International Drug Name Search
Uncough may be available in the countries listed below.
Cloperastine is reported as an ingredient of Uncough in the following countries:
International Drug Name Search
Coldacmin may be available in the countries listed below.
Chlorphenamine maleate (a derivative of Chlorphenamine) is reported as an ingredient of Coldacmin in the following countries:
Paracetamol is reported as an ingredient of Coldacmin in the following countries:
International Drug Name Search
Rivamox may be available in the countries listed below.
Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Rivamox in the following countries:
International Drug Name Search
Prémélange CS may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Colistin sulfate (a derivative of Colistin) is reported as an ingredient of Prémélange CS in the following countries:
Sulfadimethoxine is reported as an ingredient of Prémélange CS in the following countries:
International Drug Name Search
Simvastatina Asol may be available in the countries listed below.
Simvastatin is reported as an ingredient of Simvastatina Asol in the following countries:
International Drug Name Search
Penilan may be available in the countries listed below.
Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Penilan in the following countries:
Clavulanic Acid is reported as an ingredient of Penilan in the following countries:
International Drug Name Search
SPMC Promethazine HCl may be available in the countries listed below.
Promethazine hydrochloride (a derivative of Promethazine) is reported as an ingredient of SPMC Promethazine HCl in the following countries:
International Drug Name Search
Tinium may be available in the countries listed below.
Tiemonium Methylsulfate is reported as an ingredient of Tinium in the following countries:
International Drug Name Search
Coccidex may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Sulfadimethoxine sodium (a derivative of Sulfadimethoxine) is reported as an ingredient of Coccidex in the following countries:
International Drug Name Search
Rumicox may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Decoquinate is reported as an ingredient of Rumicox in the following countries:
International Drug Name Search
Sorbangil may be available in the countries listed below.
Isosorbide Dinitrate is reported as an ingredient of Sorbangil in the following countries:
International Drug Name Search
Star Iodocare may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Povidone-Iodine is reported as an ingredient of Star Iodocare in the following countries:
International Drug Name Search
Enalapril Domesco may be available in the countries listed below.
Enalapril is reported as an ingredient of Enalapril Domesco in the following countries:
International Drug Name Search
Doliv may be available in the countries listed below.
Biphenyl dimethyl dicarboxylate is reported as an ingredient of Doliv in the following countries:
International Drug Name Search
Lanodil may be available in the countries listed below.
Diltiazem hydrochloride (a derivative of Diltiazem) is reported as an ingredient of Lanodil in the following countries:
International Drug Name Search
Flebocortid may be available in the countries listed below.
Hydrocortisone 21-(sodium succinate) (a derivative of Hydrocortisone) is reported as an ingredient of Flebocortid in the following countries:
International Drug Name Search
Xylasol may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Xylazine hydrochloride (a derivative of Xylazine) is reported as an ingredient of Xylasol in the following countries:
International Drug Name Search
Zofistar may be available in the countries listed below.
Zofenopril is reported as an ingredient of Zofistar in the following countries:
Zofenopril calcium salt (a derivative of Zofenopril) is reported as an ingredient of Zofistar in the following countries:
International Drug Name Search
Pizotyline may be available in the countries listed below.
Pizotyline (USAN) is also known as Pizotifen (Rec.INN)
International Drug Name Search
Glossary
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
Zumba may be available in the countries listed below.
Yohimbine hydrochloride (a derivative of Yohimbine) is reported as an ingredient of Zumba in the following countries:
International Drug Name Search
Fegenor may be available in the countries listed below.
Fenofibrate is reported as an ingredient of Fegenor in the following countries:
International Drug Name Search
Heparina Sodica Mayne may be available in the countries listed below.
Heparin sodium salt (a derivative of Heparin) is reported as an ingredient of Heparina Sodica Mayne in the following countries:
International Drug Name Search
Magnezyum Sulfat may be available in the countries listed below.
Magnesium Sulfate is reported as an ingredient of Magnezyum Sulfat in the following countries:
International Drug Name Search
Quanox may be available in the countries listed below.
Ivermectin is reported as an ingredient of Quanox in the following countries:
International Drug Name Search
Indomethacin Sodium (USAN) is also known as Indometacin (Rec.INN)
International Drug Name Search
Glossary
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
Vincamina may be available in the countries listed below.
Vincamina (DCIT) is also known as Vincamine (Rec.INN)
International Drug Name Search
Glossary
| DCIT | Denominazione Comune Italiana |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
Arianna may be available in the countries listed below.
Ethinylestradiol is reported as an ingredient of Arianna in the following countries:
Gestodene is reported as an ingredient of Arianna in the following countries:
International Drug Name Search
Renitec comp. may be available in the countries listed below.
Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Renitec comp. in the following countries:
Hydrochlorothiazide is reported as an ingredient of Renitec comp. in the following countries:
International Drug Name Search
Zincas may be available in the countries listed below.
Zinc Aspartate is reported as an ingredient of Zincas in the following countries:
International Drug Name Search
Tegaserod Richet may be available in the countries listed below.
Tegaserod maleate (a derivative of Tegaserod) is reported as an ingredient of Tegaserod Richet in the following countries:
International Drug Name Search
Nilzan may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Levamisole hydrochloride (a derivative of Levamisole) is reported as an ingredient of Nilzan in the following countries:
Oxyclozanide is reported as an ingredient of Nilzan in the following countries:
International Drug Name Search
Tabiflex may be available in the countries listed below.
Diclofenac diethylamine (a derivative of Diclofenac) is reported as an ingredient of Tabiflex in the following countries:
International Drug Name Search
Humulin M may be available in the countries listed below.
Insulin Injection, Biphasic Isophane human (a derivative of Insulin Injection, Biphasic Isophane) is reported as an ingredient of Humulin M in the following countries:
International Drug Name Search
Omeprazol Combino Pharm may be available in the countries listed below.
Omeprazole is reported as an ingredient of Omeprazol Combino Pharm in the following countries:
International Drug Name Search
Zecken-Floh-Band may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Stirofos is reported as an ingredient of Zecken-Floh-Band in the following countries:
International Drug Name Search
Risperidone-Arrow 1 may be available in the countries listed below.
Risperidone is reported as an ingredient of Risperidone-Arrow 1 in the following countries:
International Drug Name Search
Katehat may be available in the countries listed below.
Oxprenolol hydrochloride (a derivative of Oxprenolol) is reported as an ingredient of Katehat in the following countries:
International Drug Name Search
Eutac may be available in the countries listed below.
Moclobemide is reported as an ingredient of Eutac in the following countries:
International Drug Name Search
Tolindol may be available in the countries listed below.
Proglumetacin dimaleate (a derivative of Proglumetacin) is reported as an ingredient of Tolindol in the following countries:
International Drug Name Search
In the US, Zocor (simvastatin systemic) is a member of the drug class statins and is used to treat High Cholesterol, High Cholesterol - Familial Heterozygous, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa - Elevated LDL, Hyperlipoproteinemia Type IIb - Elevated LDL VLDL, Hyperlipoproteinemia Type III - Elevated beta-VLDL IDL and Hyperlipoproteinemia Type IV - Elevated VLDL.
US matches:
UK matches:
Simvastatin is reported as an ingredient of Zocor in the following countries:
International Drug Name Search
Glossary
| SPC | Summary of Product Characteristics (UK) |
Maxifloxina may be available in the countries listed below.
Ofloxacin is reported as an ingredient of Maxifloxina in the following countries:
International Drug Name Search
Zespira may be available in the countries listed below.
Montelukast sodium salt (a derivative of Montelukast) is reported as an ingredient of Zespira in the following countries:
International Drug Name Search
Guaïazulène may be available in the countries listed below.
Guaïazulène (DCF) is also known as Guaiazulene
International Drug Name Search
Glossary
| DCF | Dénomination Commune Française |
In the US, Iquix (levofloxacin ophthalmic) is a member of the drug class ophthalmic anti-infectives and is used to treat Conjunctivitis - Bacterial and Ophthalmic Surgery.
US matches:
Levofloxacin is reported as an ingredient of Iquix in the following countries:
International Drug Name Search
Soligental may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Gentamicin sulfate (a derivative of Gentamicin) is reported as an ingredient of Soligental in the following countries:
International Drug Name Search
In some countries, this medicine may only be approved for veterinary use.
Ivermectin is reported as an ingredient of Zimecterin Gold in the following countries:
Praziquantel is reported as an ingredient of Zimecterin Gold in the following countries:
International Drug Name Search
Meaverin Actavis may be available in the countries listed below.
Mepivacaine hydrochloride (a derivative of Mepivacaine) is reported as an ingredient of Meaverin Actavis in the following countries:
International Drug Name Search
Let Lit may be available in the countries listed below.
Pindolol is reported as an ingredient of Let Lit in the following countries:
International Drug Name Search
Zodalin may be available in the countries listed below.
Dihydroergotoxine mesilate (a derivative of Dihydroergotoxine) is reported as an ingredient of Zodalin in the following countries:
International Drug Name Search
Halgeze may be available in the countries listed below.
Ketorolac is reported as an ingredient of Halgeze in the following countries:
International Drug Name Search
Natrium Salicylicum Biotika may be available in the countries listed below.
Salicylic Acid sodium (a derivative of Salicylic Acid) is reported as an ingredient of Natrium Salicylicum Biotika in the following countries:
International Drug Name Search
Zeefra may be available in the countries listed below.
Cefradine is reported as an ingredient of Zeefra in the following countries:
International Drug Name Search
Folicron may be available in the countries listed below.
Ferrous Sulfate is reported as an ingredient of Folicron in the following countries:
Folic Acid is reported as an ingredient of Folicron in the following countries:
Metoclopramide is reported as an ingredient of Folicron in the following countries:
International Drug Name Search
Erycinum may be available in the countries listed below.
Erythromycin lactobionate (a derivative of Erythromycin) is reported as an ingredient of Erycinum in the following countries:
International Drug Name Search
Cyprene-35 ED may be available in the countries listed below.
Cyproterone 17α-acetate (a derivative of Cyproterone) is reported as an ingredient of Cyprene-35 ED in the following countries:
Ethinylestradiol is reported as an ingredient of Cyprene-35 ED in the following countries:
International Drug Name Search
Teneretic may be available in the countries listed below.
Atenolol is reported as an ingredient of Teneretic in the following countries:
Chlortalidone is reported as an ingredient of Teneretic in the following countries:
International Drug Name Search
Zofixi may be available in the countries listed below.
Cefixime is reported as an ingredient of Zofixi in the following countries:
International Drug Name Search
Terbutalina may be available in the countries listed below.
Terbutalina (DCIT) is known as Terbutaline in the US.
International Drug Name Search
Glossary
| DCIT | Denominazione Comune Italiana |
Acido Ascorbico Lachifarma may be available in the countries listed below.
Ascorbic Acid is reported as an ingredient of Acido Ascorbico Lachifarma in the following countries:
International Drug Name Search
Zevalin Indium may be available in the countries listed below.
Ibritumomab Tiuxetan is reported as an ingredient of Zevalin Indium in the following countries:
International Drug Name Search
Flumetol may be available in the countries listed below.
Fluorometholone is reported as an ingredient of Flumetol in the following countries:
Fluorometholone 17-acetate (a derivative of Fluorometholone) is reported as an ingredient of Flumetol in the following countries:
International Drug Name Search
In the US, Nupercainal (dibucaine topical) is a member of the drug class topical anesthetics and is used to treat Anal Itching, Burns - External, Hemorrhoids and Local Anesthesia.
US matches:
Cinchocaine is reported as an ingredient of Nupercainal in the following countries:
Cinchocaine hydrochloride (a derivative of Cinchocaine) is reported as an ingredient of Nupercainal in the following countries:
International Drug Name Search
Zencef may be available in the countries listed below.
Cefuroxime sodium salt (a derivative of Cefuroxime) is reported as an ingredient of Zencef in the following countries:
International Drug Name Search
Nopron may be available in the countries listed below.
Niaprazine is reported as an ingredient of Nopron in the following countries:
International Drug Name Search
Oxolamina may be available in the countries listed below.
Oxolamina (DCIT) is also known as Oxolamine (Rec.INN)
International Drug Name Search
Glossary
| DCIT | Denominazione Comune Italiana |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
Azibax may be available in the countries listed below.
Azithromycin is reported as an ingredient of Azibax in the following countries:
International Drug Name Search
Sparcin may be available in the countries listed below.
Sparfloxacin is reported as an ingredient of Sparcin in the following countries:
International Drug Name Search
Ziprasidone Mesylate may be available in the countries listed below.
Ziprasidone Mesylate (USAN) is known as Ziprasidone in the US.
International Drug Name Search
Glossary
| USAN | United States Adopted Name |
Norbal may be available in the countries listed below.
Buspirone hydrochloride (a derivative of Buspirone) is reported as an ingredient of Norbal in the following countries:
International Drug Name Search
Vasodyl may be available in the countries listed below.
Carvedilol is reported as an ingredient of Vasodyl in the following countries:
International Drug Name Search
Flutivate may be available in the countries listed below.
Fluticasone propionate (a derivative of Fluticasone) is reported as an ingredient of Flutivate in the following countries:
International Drug Name Search
There are currently no drugs listed for "Tuberculosis, Urinary Tract".
Micromedex Care Notes:
Medical Encyclopedia:
Luoji may be available in the countries listed below.
Netilmicin sulfate (a derivative of Netilmicin) is reported as an ingredient of Luoji in the following countries:
International Drug Name Search
In the US, Zenchent (ethinyl estradiol/norethindrone systemic) is a member of the following drug classes: contraceptives, sex hormone combinations and is used to treat Birth Control.
US matches:
Ethinylestradiol is reported as an ingredient of Zenchent in the following countries:
Norethisterone is reported as an ingredient of Zenchent in the following countries:
International Drug Name Search
Isopto Carpine is a brand name of pilocarpine ophthalmic, approved by the FDA in the following formulation(s):
No. There is currently no therapeutically equivalent version of Isopto Carpine available.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Isopto Carpine. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: About generic drugs.
There are no current U.S. patents associated with Isopto Carpine.
Triastonal may be available in the countries listed below.
Sitosterol, β- is reported as an ingredient of Triastonal in the following countries:
International Drug Name Search
Zinksulfaat may be available in the countries listed below.
Zinc Sulfate is reported as an ingredient of Zinksulfaat in the following countries:
International Drug Name Search
Zoltis may be available in the countries listed below.
Zolpidem tartrate (a derivative of Zolpidem) is reported as an ingredient of Zoltis in the following countries:
International Drug Name Search
Zanitra may be available in the countries listed below.
Folic Acid is reported as an ingredient of Zanitra in the following countries:
International Drug Name Search
Lostin may be available in the countries listed below.
Lovastatin is reported as an ingredient of Lostin in the following countries:
International Drug Name Search
Lubri-K may be available in the countries listed below.
Diclofenac is reported as an ingredient of Lubri-K in the following countries:
International Drug Name Search
Zaditen SRO may be available in the countries listed below.
Ketotifen fumarate (a derivative of Ketotifen) is reported as an ingredient of Zaditen SRO in the following countries:
International Drug Name Search
Permitabs may be available in the countries listed below.
Potassium Permanganate is reported as an ingredient of Permitabs in the following countries:
International Drug Name Search
Vioses may be available in the countries listed below.
Sildenafil citrate (a derivative of Sildenafil) is reported as an ingredient of Vioses in the following countries:
International Drug Name Search
Hyoscine Methobromide may be available in the countries listed below.
Hyoscine Methobromide (BAN, BANM) is known as Scopolamine in the US.
International Drug Name Search
Glossary
| BAN | British Approved Name |
| BANM | British Approved Name (Modified) |
Cilinafosal may be available in the countries listed below.
Ephedrine hydrochloride (a derivative of Ephedrine) is reported as an ingredient of Cilinafosal in the following countries:
Sulfanilamide sodium mesylate (a derivative of Sulfanilamide) is reported as an ingredient of Cilinafosal in the following countries:
International Drug Name Search
Zitroken may be available in the countries listed below.
Azithromycin dihydrate (a derivative of Azithromycin) is reported as an ingredient of Zitroken in the following countries:
International Drug Name Search
Zinadol may be available in the countries listed below.
Cefuroxime axetil (a derivative of Cefuroxime) is reported as an ingredient of Zinadol in the following countries:
International Drug Name Search
Generic Name: divalproex sodium (Oral route)
dye-VAL-proe-ex SOE-dee-um
Hepatotoxicity (some cases fatal), usually occurring during the first 6 months of treatment, has been reported in patients receiving valproic acid and its derivatives. Children under the age of two years are at a considerably increased risk of developing fatal hepatotoxicity. Monitor patients closely, and perform liver function tests prior to therapy and at frequent intervals thereafter. Valproate can produce teratogenic effects such as neural tube defects (eg, spina bifida). Accordingly, the use of divalproex sodium in women of childbearing potential requires that the benefits of its use be weighed against the risk of injury to the fetus. Life-threatening pancreatitis has been reported in both children and adults receiving valproate. If pancreatitis is diagnosed, valproate should ordinarily be discontinued .
In the U.S.
In Canada
Available Dosage Forms:
Therapeutic Class: Anticonvulsant
Pharmacologic Class: Valproic Acid
Chemical Class: Valproic Acid
Divalproex sodium is used alone or together with other medicines to control certain types of seizures (convulsions) in the treatment of epilepsy. This medicine is an anticonvulsant that works in the brain tissue to stop seizures.
Divalproex sodium is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches.
This medicine is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of divalproex sodium in children. However, safety and efficacy have not been established in children below 10 years of age. Because of divalproex sodium's toxicity, use in children below 2 years of age requires extreme caution.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of divalproex sodium in the elderly. However, elderly patients are more likely to have unwanted effects (e.g., tremors or unusual drowsiness), which may require an adjustment in the dose for patients receiving divalproex sodium.
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | D | Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. |
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
This section provides information on the proper use of a number of products that contain divalproex sodium. It may not be specific to Depakote ER. Please read with care.
Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To keep blood levels constant, take this medicine at the same time each day and do not miss any doses.
This medicine comes with a medication guide and patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.
You may take this medicine with food to avoid stomach upset.
The sprinkle capsules may be opened and the contents may be sprinkled onto soft food such as applesauce or pudding. This mixture must be swallowed immediately without chewing and followed with a glass of water to ensure complete swallowing of the sprinkles.
Swallow the extended release tablet whole with a full glass of water. Do not split, crush, or chew it.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
It is very important that your doctor check your progress closely while you are using this medicine to see if it is working properly and to allow for a change in the dose. Blood tests may be needed to check for any unwanted effects.
Using this medicine while you are pregnant (especially during first trimester) can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
It is very important to take folic acid before getting pregnant and during early pregnancy to lower chances of harmful side effects to your unborn baby. Ask your doctor or pharmacist for help if you are not sure how to choose a folic acid product.
Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: abdominal pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin.
Pancreatitis may occur while you are using this medicine. Tell your doctor right away if you have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness.
Check with your doctor right away if you are having unusual drowsiness, dullness, tiredness, weakness or feelings of sluggishness, changes in mental status, or vomiting. These may be symptoms of a serious condition called hyperammonemic encephalopathy.
Divalproex sodium may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.
Do not stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping completely.
Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.
Check with your doctor right away if you have unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness; confusion; low body temperature; or loss of consciousness while taking this medicine.
This medicine may cause serious allergic reactions that affect several parts of the body (e.g., liver or kidney). Check with your doctor right away if you have more than one of the following symptoms: fever; dark urine; headache; rash; stomach pain; swollen lymph glands in the neck, armpit, or groin; unusual tiredness; or yellow eyes or skin.
Divalproex sodium may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you notice any of these adverse effects, tell your doctor right away.
This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates or medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are taking this medicine.
If you are taking the sprinkle capsules, part of the capsules may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Depakote ER side effects (in more detail)
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